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Human Soluble tumor necrosis factor receptor 2 (sTNF-R2) ELISA Kit

Human Soluble tumor necrosis factor receptor 2 (sTNF-R2) ELISA Kit

Cat no: KTE60215

Supplier: Abbkine Scientific Co.Ltd.
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Soluble tumor necrosis factor receptor 2 (sTNF-R2) is a member of the TNF-receptor superfamily. sTNF-R2 and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Catalogue number: KTE60215
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P20333
Gene: 7133
Additional info: Human Soluble tumor necrosis factor receptor 2 (sTNF-R2) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFRSF1B. No significant cross-reactivity or interference between Human TNFRSF1B and analogues was observed.

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