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Human Sulfatase-modifying factor 1 (SUMF1) ELISA Kit

Human Sulfatase-modifying factor 1 (SUMF1) ELISA Kit

Cat no: KTE60403

Supplier: Abbkine Scientific Co.Ltd.
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Sulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine (FGly), the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme (FGE), in the endoplasmic reticulum (ER). The genetic defect of FGly formation caused by mutations in the SUMF1 gene results in multiple sulfatase deficiency (MSD), a lysosomal storage disorder (Roeser et al., 2006).Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart.
Catalogue number: KTE60403
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q8NBK3
Gene: 285362
Additional info: Human Sulfatase-modifying factor 1 (SUMF1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SUMF1. No significant cross-reactivity or interference between Human SUMF1 and analogues was observed.

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