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Human Transcription termination factor 1 (TTF1) ELISA Kit

Cat no: KTE60119

Human Transcription termination factor 1 (TTF1) ELISA Kit

TTF2 has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.The deduced 990-amino acid TTF2 protein shares 43% amino acid sequence identity with Drosophila factor 2. These proteins contain 7 motifs found in helicase superfamilies 1 and 2; 7 additional motifs shared only by SWI2/SNF2 family members; and 3 conserved motifs and a nuclear localization signal that are not conserved among the SWI2/SNF2 family. Similar to Drosophila factor 2, recombinant human TTF2 displayed a strong double-stranded DNA-dependent ATPase activity that was inhibited by single-stranded DNA and exhibited RNA polymerase II termination activity.

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SPECIFICATIONS

Catalog Number

KTE60119

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7270

Accession

Q15361

Additional Info

Human Transcription termination factor 1 (TTF1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TTF1. No significant cross-reactivity or interference between Human TTF1 and analogues was observed.

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