Catalogue number: | 13782 |
Hosts: | Rabbit |
Applications: | Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | synthetic peptides from human I2PP2A/SET amino acids 79-94 and 148-164 |
P type: | Antibodies |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | I2PP2A/SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly, and histone binding. The SET gene produces two isoforms from transcript variants. Isoform 1 and 2 interact directly with each other and with ANP32A within the tripartite inhibitor of acetyltransferases (INHAT) complex, inhibiting EP300/CREBBP and PCAF-mediated acetylation of histones. The two isoforms differ in their amino termini but are identical through the regions used as antigens for preparing this antibody. |