

Supplier:
Cayman Chemical CompanyCat no: 10008207
IGFBP5 Polyclonal Antibody
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SPECIFICATIONS
Catalog Number
10008207
Applications
WB
Hosts
Rabbit
Form
1 ea
P Type
Antibodies
Weight
0
Antigen
human IGFBP5 amino acids 192-206 (CRRHMEASLQELKAS)
Storage Temp
-20
Shipping Temp
-20
Additional Info
Insulin-like growth factor binding protein 5 (IGFBP5) is a secreted protein that binds IGF-1 and restricts it from accessing its cell-surface receptor (IGF-1R). This aids in regulation of cell growth, differentiation, and apoptosis. IGFBP5 also displays IGF-1 independent transactivational activity in the nucleus. Some tissues and cell types with higher levels of this protein include kidney, heart, placenta, and skeletal cells. Expression has also been reported in a variety of cancers, including mammary gland and neuroblastoma. IGFBP5 (272 amino acids) has a calculated molecular weight of 30.6 kDa. Reported glycosylation and phosphorylation sites may explain the band migration to 33 kDa.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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