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Insulin-Like Growth Factor Binding Protein 2 (IGFBP2, BP2, IBP2)

Cat no: I7661-16G8

Insulin-Like Growth Factor Binding Protein 2 (IGFBP2, BP2, IBP2)

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.\n\nApplications: \nOther applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I7661-16G8

Size

1mg

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in 0.1M Tris-HCl, pH 7.5.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Additional Info

Recognizes human IGFBP-2

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