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Interferon alpha 1, Recombinant, Human (IFNa)

Cat no: I7661-90

Interferon alpha 1, Recombinant, Human (IFNa)

Interferon-alpha is cytokines that are widely known to induce potent anti-viral activity . Interferon-alpha exerts a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. \n\nRecombinant human Interferon-alpha was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.\n \nMolecular Weight: 19.5kD (167 amino acids)\n \nSequence: \nMCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNVDSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM/RSLSLSTNLQ ERLRRKE\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I7661-90

Size

100ug

Form

Supplied as a liquid in PBS, pH 7.4

Purity

(same/more than) 95% by SDS PAGE

References

1. Goeddel DV, et al. (1981) Nature, 290(5801): 20-6 2. Mire-Sluis, A.R., et al.(1996) J. Immunol. Methods.195: 55-61 3. Rubinstein, S., et al.(1981) J. Virol. 37: 755-758

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