Supplier:
Cayman Chemical CompanyCat no: 583311
Interleukin-1(beta) (human) EIA Kit
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SPECIFICATIONS
Catalog Number
583311
Form
96 Well
P Type
Assay Kits|Cytokines
Weight
0
Storage Temp
-20
Shipping Temp
-20
Additional Info
Interleukin 1 (IL-1) is a name for a family of proteins which includes IL-1(alpha), IL-1(beta), ILra (Interleukin receptor antagonist) and IL-18. IL-1(beta) is synthesized as 269 amino acid pro-cytokine that is enzymatically cleaved by IL-1(beta)-converting enzyme (ICE) into the active 154 amino acid, 17 kDa peptide mature peptide. IL-1(beta) is produced by many cell types including macrophages, monocytes, astrocytes, endothelial cells, smooth muscle cells, keratinocytes, adipocytes, T cells, and eosinophils. Although IL-1(alpha) and IL-1(beta) exhibit only 26% amino acid identity, they bind to the same cell-surface receptors, IL-1 RI and IL-1 RII, present on a variety of cell types involved in immune or inflammatory responses. Normal production of IL-1 is critical for mediating host responses to infection and injury. Disease states in which IL-1 actively participates include inflammatory diseases, such as arthritis, inflammatory bowel disease, and shock, as well as arteriosclerosis, allergic disease, and some types of cancer.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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