Interleukin-17A (IL-17A or CTLA-8) is produced by TH17 cells, a helper CD4 T cell lineage distinct from TH1 (producing IFN(gamma)) and TH2 (producing IL-4, IL-5, and IL-13). IL-17A acts in a variety of cell types to induce the production of acute-phase proteins, antimicrobial proteins, and neutrophil-activating factors. It is especially important for antimicrobial responses and plays a role in the pathogenesis of several mouse models of human chronic inflammatory disease including collagen induced arthritis, experimental autoimmune encephalomyelitis, and asthma. Cayman's IL-17A (mouse) EIA Kit is an immunometric (i.e., sandwich) EIA that permits IL-17A measurements within the range of 0-1,000 pg/ml, with a lower limit of quantification (LLOQ) of 15.6 pg/ml.