Catalogue number: |
SMC-388D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S24-18 |
Accession: |
NP_001007236.1 |
Gene: |
25262 |
Swiss prot: |
P29994 |
Dilutions: |
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
Form: |
Protein G purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-388 was sufficient for detection of IP3 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Inositol 1,4,5-triphosphate receptor, also known as IP3R or InsP3R, is a member of the intracellular calcium release
channel family, and is located in the endoplasmic reticulum.
It functions as a Ca2+ release channel for intracellular stores
of calcium io |
Alternative names: |
IP3 Receptor, S24-18 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd
Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Joseph S.K. (1996) Cell Signal 8: 1-7.
4. Galvan D.L., et al. (1999) J Biol Chem 274: 29483-29492.
5. Haug L.S., et al. |