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IP6K2 Monoclonal Antibody (Clone 4F10)

Cat no: 10239

IP6K2 Monoclonal Antibody (Clone 4F10)

Summary: Antigen: human IP6K2 . Host: mouse, clone 4F10 . Isotype: IgG2bk . Cross Reactivity: (+) human and mouse IP6K2 . Application(s): ICC and WB . IP6K2 is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP. IP6K2 functions as a proapoptotic protein kinase and binds to tumor necrosis factor receptor-associated factor 2 and inhibits NF-kB signaling.

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SPECIFICATIONS

Catalog Number

10239

Applications

ICC, WB

Hosts

Mouse

Form

1 ea

P Type

Antibodies|Intracellular Signaling

Weight

0

Isotype

IgG2bk

Storage Temp

-20

Shipping Temp

-20

Additional Info

Inositol hexakisphosphate kinase 2 (IP6K2) is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP. IP6K2 functions as a proapoptotic protein kinase. IP6K2 binds to tumor necrosis factor receptor-associated factor 2 and inhibits NF-kB signaling. Heat Shock Protein 90 regulates apoptosis through a normal physiological interaction with IP6K2 by inhibiting its catalytic activity. Thus, IP6K2 is a potential target for cancer therapeutics development.

SUPPLIER INFO

Cayman Chemical Company

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