Deuterated Irinotecan, a DNA topoisomerase inhibitor.
Melting Point:
258-260 degrees C
Solubility:
DMSO, Methanol (sparingly)
Method for Determining Identity:
Proton Spectroscopic and Mass Spectrometric Analysis
TLC Conditions:
SiO2; Dichloromethane:
Methanol; 7:3 Visualized with UV and AMCS; Single spot; Rf=0.5.
Chlorine Content: 6.6%
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.