ISOkine™ are the world’s first biorisk-free growth factors and cytokines.
Produced in the proficient Orfeus™ system, using barley grain as a vehicle for high-throughput production of recombinant proteins, ISOkine™ is a new option for basic and applied medical research, cell culture media and diagnostics.
ORF Genetics offers now for the first time biorisk-free ISOkine™ mouse LIF (leukemia inhibitory factor, myeloid leukemia inhibitory factor for embryonic stem cell research.
mLIF a pleiotropic lymphoid factor was initially described as a factor that inhibits the proliferation of myeloid leukemia cells and induces their differentiation into macrophages.
Other activities of LIF include inhibition of adipogenesis, cholinergic neuron differentiation and bone metabolism.