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JARID1B/PLU1 (C-Term) Polyclonal Antibody

Cat no: 14701

JARID1B/PLU1 (C-Term) Polyclonal Antibody

Antigen: human JARID1B/PLU1 amino acids 1,534-1,544 . Host: rabbit . Cross Reactivity: (+) human JARID1B/PLU1 . Application(s): FC and ICC

Prices direct from Cayman Chemical Company

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SPECIFICATIONS

Catalog Number

14701

Applications

FC, ICC

Hosts

Rabbit

Form

1 ea

P Type

Demethylase|Antibodies

Weight

0

Antigen

human JARID1B/PLU1 amino acids 1,534-1,544

Storage Temp

-20

Shipping Temp

-20

Additional Info

Jumonji AT rich interactive domain 1B (JARID1B) nuclear proteins are potential histone demethylases. JARID1B demethylation of Lys-4 of histone H3 plays an important role in breast cancer cell proliferation through BRCA1 repression. JARID1B acts as a transcriptional co-repressor of two developmental transcription factors, PAX-9 and BF1, which are crucial for organogenesis in mouse embryo. JARID1B has also been shown to interact directly with histone deacetylase.

SUPPLIER INFO

Cayman Chemical Company

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