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Products JARID1B/PLU1 (C-Term) Polyclonal Antibody
| Catalogue number: | 14701 |
| Hosts: | Rabbit |
| Applications: | Flow Cytometry, Immunocytochemistry |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | human JARID1B/PLU1 amino acids 1,534-1,544 |
| P type: | Demethylase|Antibodies |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Jumonji AT rich interactive domain 1B (JARID1B) nuclear proteins are potential histone demethylases. JARID1B demethylation of Lys-4 of histone H3 plays an important role in breast cancer cell proliferation through BRCA1 repression. JARID1B acts as a transcriptional co-repressor of two developmental transcription factors, PAX-9 and BF1, which are crucial for organogenesis in mouse embryo. JARID1B has also been shown to interact directly with histone deacetylase. |
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