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Products JC-1 Mitochondrial Membrane Potential Assay Kit
| Catalogue number: | 10009172 |
| Weight: | 0 |
| Form: | 1 ea |
| P type: | Assay Kits |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Mitochondrial membrane potential, .DELTA..psi.m, is an important parameter of mitochondrial function used as an indicator of cell health. JC-1 is a lipophilic, cationic dye that can selectively enter into mitochondria and reversibly change color from green to red as the membrane potential increases. In healthy cells with high mitochondrial .DELTA..psi.m, JC-1 spontaneously forms complexes known as J-aggregates with intense red fluorescence. On the other hand, in apoptotic or unhealthy cells with low .DELTA..psi.m, JC-1 remains in the monomeric form, which shows only green fluorescence. Cayman's JC-1 Mitochondrial Membrane Potential Assay Kit provides all the necessary reagents, as well as complete instructions, for analysis of mitochondrial integrity in whole cells. The assay is applicable to flow cytometry, fluorescence microscopy, and 96-well plate formats. |
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