Catalogue number: | 10382 |
Hosts: | Rabbit |
Applications: | Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | human recombinant JMJD2A amino acids 1-350 Human recombinant JMJD2A amino acids 1-350 |
P type: | Antibodies|Demethylase |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | Jumonji Domain Containing 2A (JMJD2A) is a lysine specific demethylase with emerging roles in histone modification or epigenetic remodeling. This JMJD2A polyclonal antibody was raised against an N-terminal recombinant fragment of JMJD2A. This fragment includes amino acids 1-350 including the JMJN and JMJC domains but not the two LAP/PHD zinc finger or Tudor domains of the 1,064 amino acid protein. JMJD2A is detected at 135 kDa by western blotting using a DLD1 cell lysate as a positive control. Also, the expression of JMJD2A varies by tissue, and northern blotting suggests skeletal muscle as a negative control and lung as a positive control tissue. |