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KA2 (Kainate Receptor)

Cat no: K0002

KA2 (Kainate Receptor)

Glutamate receptors are the major excitatory neurotransmitter receptors in the central nervous system (CNS). They play critical roles in the mechanisms of synaptic plasticity, in the development of the nervous system and have been suggested to be involved in the neuronal cell death that occurs in several neuropathological conditions. KA2 is a member of the kainate ionotropic receptors. Kainate receptors mediate fast excitatory synaptic transmissions, are rapidly activated and desensitized by glutamate and are mainly permeable to Na+ and K+.\n\nApplications: \nSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-2ug/ml detects KA2 from rat brain microsomal preparation.\nImmunoprecipitation: 4ug immunoprecipitates KA2 from 500ug rabbit brain membrane extract.\nImmunohistochemistry: 1ug/ml detects KA2 in formalin-fixed, paraffin-embedded rat brain sections using high energy antigen retrieval.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability: \nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

K0002

Size

200ug

Applications

IHC, IP, WB

Hosts

Rabbit

Reactivities

Rat, Rabbit

Form

Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.150M sodium chloride, 0.05% sodium azide, 30% glycerol.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

References

1. Herb, A., et al., Neuron 8: 775-785 (1992).

Additional Info

Recognizes rat KA2, Mr~123kD (Kainate Receptor). Species Crossreactivity: Rabbit.

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Applications

FC

Hosts

Mouse

Reactivities

Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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