KIR2DL3 (Killer Cell Immunoglobulin-like Receptor Two Domains Long Cytoplasmic Tail 3, Killer Cell Immunoglobulin Like Receptor 2DL3, CD158 Antigen-like Family Member B2, CD158b2, CD158b, GL183, Killer Inhibitory Receptor cl 2-3, KIRCL23, KIR-023GB, KIR-K

Applications: \nSuitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution: \nFlow Cytometry: 1:10-1:50 10ul labels 10e6 cells in 100ul. \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

C2548-87D

Size

200ug

Applications

FC, IP

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Moretta, A. et al. (1990). A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. J. Exp. Med. 171:695-714. 2. Moretta, A. et al. (1993). p58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC Class-1 protected cells in NK clones dislaying different specificites. J. Exp. Med. 178:597-604. 3. Ciccore, E. et al. (1992). Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans. J. Exp. Med. 175:709-718. 4. Moretta, A. et al. (1997). Major histocompatibility complex class I - specific receptors on human natural killer and T lymphocytes. Immunol Rev. 155:105-117. 5. Moretta, A. et al. (1995). Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J. Exp. Med. 182:875-884. 6. Biassoni, R. et al. (1996). The human leucocyte antigen (HLA)-c- specific \"Activatory\" or \"Inhibitory\" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J. Exp. Med. 183: 645-650.\n7. Long, E.O. et al. (1996). inhibitory MHC Class I receptors on NK and T cells: a standard nomenclature. Immunol. Today 17:106.

Additional Info

Recognizes human CD158b at ~58kD.

Alternative Names

NKAT