Catalogue number: |
SMC-387D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S23-27 |
Accession: |
NP-002223.3 |
Gene: |
3738 |
Swiss prot: |
P22001 |
Dilutions: |
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG2A |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-387 was sufficient for detection of Kv1.3 in 20ug of rat brain lysate by colorimetric
immunoblot analysis using goat anti-mouse IgG:HRP
as the secondary antibody. |
Scientific background: |
Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pole. Each alphasubunit
consists of six transmembrane segments with
cytoplasmic NH2 and COOH-termini. Members of the KV1-4
subfamilies generate functional K+ |
Alternative names: |
HGK5, HLK3, HPCN3, KCNA3, MK3, PCN3 |
References: |
Bocksteins E., et al. (2009) Am J Physiol. 296:C1271-1278. |