Catalogue number: |
SMC-377D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S75-41 |
Accession: |
NP_113927.2 |
Gene: |
65195 |
Swiss prot: |
Q62897 |
Dilutions: |
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-377 was sufficient for detection of Kv4.3 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Potassium volgate-gated channel subfamily D member 3 (also knowns as Kv4.3) is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phas |
Alternative names: |
Kv4.3, Kcnd3 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Postma A.V., et al. (2000) Hum Genet. 106(6): 614-619.
4. Gutman G.A., et al. (2005) Pharmacol Rev. 57(4): 473-508.
5. O |