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Products Leukotriene B4 Express EIA Kit
| Catalogue number: | 10009292 |
| Weight: | 0 |
| Form: | 96 Well |
| P type: | Assay Kits|Eicosanoids|Leukotrienes |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | LTB4 stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. Plasma levels of LTB4 increase from <100 pg/ml to >100 ng/ml following leukocyte stimulation. LTB4 is metabolized in leukocytes and hepatocytes to less active 20-hydroxy and 20-carboxy LTB4 and then further oxidized to ?-carboxy dinor LTB4 and ?-carboxy tetranor-LTB3. LTB4 is not excreted in the urine. Cayman's LTB4 Express EIA Kit is a competitive assay that can be used for quantification of LTB4 in plasma and other sample matrices. The EIA typically displays an IC50 (50% B/B0) of approximately 150 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml. |
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