Leukotriene B4 Express EIA Kit

LTB4 stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. LTB4 is metabolized in leukocytes and hepatocytes to less active 20-hydroxy and 20-carboxy LTB4 and then further oxidized to ?-carboxy dinor LTB4 and ?-carboxy tetranor-LTB3. It is not excreted in the urine. Cayman's LTB4 Express EIA Kit is a competitive assay that can be used for quantification of LTB4 in plasma and other sample matrices. The EIA typically displays an IC50 (50% B/B0) of approximately 150 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.

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SPECIFICATIONS

Catalog Number

10009292

Form

96 Well

P Type

Assay Kits|Eicosanoids|Leukotrienes

Weight

0

Storage Temp

-20

Shipping Temp

-20

Additional Info

LTB4 stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. Plasma levels of LTB4 increase from <100 pg/ml to >100 ng/ml following leukocyte stimulation. LTB4 is metabolized in leukocytes and hepatocytes to less active 20-hydroxy and 20-carboxy LTB4 and then further oxidized to ?-carboxy dinor LTB4 and ?-carboxy tetranor-LTB3. LTB4 is not excreted in the urine. Cayman's LTB4 Express EIA Kit is a competitive assay that can be used for quantification of LTB4 in plasma and other sample matrices. The EIA typically displays an IC50 (50% B/B0) of approximately 150 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.