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MafG, Recombinant, Human, aa1-162, His-tag (Transcription Factor MafG, V-maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G, hMAF)

Cat no: M1740-56

MafG, Recombinant, Human, aa1-162, His-tag (Transcription Factor MafG, V-maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G, hMAF)

MAFG, belongs to the Maf family. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.\n\nSource:\nRecombinant corresponding to aa1-162 from human MAFG, fused to His-tag at N-terminal expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MTTPNKGNKA LKVKREPGEN GTSLTDEELV TMSVRELNQH LRGLSKEEIV QLKQRRRTLK NRGYAASCRV KRVTQKEELE KQKAELQQEV EKLASENASM KLELDALRSK YEALQTFART VARSPVAPAR GPLAAGLGPL VPGKVAATSV ITIVKSKTDA RS\n\nMolecular Weight:\n~20kD (MALDI-TOF)\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

M1740-56

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 40% glycerol, 0.15M sodium chloride, 1mM DTT.

Purity

~90% (SDS-PAGE)

References

1. Hung H.-L., et al. (2001) J. Biol. Chem. 276:10715-10721 2. Blank V., et al. (1997) Genomics. 44:147-149

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SUPPLIER INFO

Applications

ELISA

Reactivities

Hum

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IF

Hosts

Mouse

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Applications

ELISA, WB

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Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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