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MAPRE3 (Microtubule-associated Protein RP/EB Family Member 3, EB1 Protein Family Member 3, EBF3, End-binding Protein 3, EB3, RP3)

Cat no: M2369-70A

MAPRE3 (Microtubule-associated Protein RP/EB Family Member 3, EB1 Protein Family Member 3, EBF3, End-binding Protein 3, EB3, RP3)

The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:16,000\nWestern Blot: 0.05-0.2ug/ml, observed in human brain (cerebellum) and Mouse Brain lysates on ~33kD bands\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

M2369-70A

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum, Mouse, Bov, Can

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

1. Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A, Mammalian end binding proteins control persistent microtubule growth. The Journal of cell biology 2009 Mar 184(5):691-706.

Additional Info

Recognizes human MAPRE3. Species Crossreactivity: Mouse. Species sequence homology: Bovine and canine.

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