MARCH9, CT (MARCH9, RNF179, E3 ubiquitin-protein ligase MARCH9, Membrane-associated RING finger protein 9, Membrane-associated RING-CH protein IX, RING finger protein 179) (FITC)

MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM].\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

038198-FITC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Nice, T.J., et al. J. Immunol. 185(9):5369-5376(2010)\nBailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)\nTalmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)\nHoer, S., et al. FEBS Lett. 581(1):45-51(2007)\nBartee, E., et al. J. Virol. 78(3):1109-1120(2004)

Additional Info

Human

Alternative Names

MARCH9, RNF179, E3 ubiquitin-protein ligase MARCH9, Membrane-associated RING finger protein 9, Membrane-associated RING-CH protein IX, RING finger protein 179