MtoZ Biolabs employs two methodologies for the analysis and evaluation of QC samples in project experiments: spectral overlay comparison and principal component analysis (PCA). The spectral overlays from the total ion chromatograms obtained by UPLC-QTOF-MS are compared, as illustrated in the figure below. The results show that the intensities and retention times of the chromatographic peaks are closely aligned, indicating minimal variability due to instrumental errors throughout the experimental process.
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