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Mn SOD (rat) Polyclonal Antibody

Cat no: 10011389

Mn SOD (rat) Polyclonal Antibody

Antigen: rat Mn SOD . Host: rabbit . Cross-reactivity: (+) human, rat, mouse, bovine, canine, chicken, Drosophila, guinea pig, porcine, hamster, monkey, rabbit, sheep, and Xenopus Mn SOD . Applications: WB, IP, IHC, and EIA . SOD2 is a manganese-containing enzyme in the mitochondrial matrix that catalyzes the dismutation of the superoxide radical O2- to O2 and H2O2.

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SPECIFICATIONS

Catalog Number

10011389

Applications

IHC, IP, WB

Hosts

Rabbit

Form

100 microL

P Type

Antibodies

Weight

25

Antigen

rat Mn SOD

Storage Temp

-20

Shipping Temp

-20

Additional Info

Superoxide dismutase (SOD) is an endogenously-produced intracellular enzyme present in almost every cell in the body. It catalyzes the dismutation of the superoxide radical O2- to O2 and H2O2. There are two main types of SOD in mammalian cells. One form, SOD1, contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cystines forming an intra-subunit disulphide bridge. The second form, SOD2, is a manganese-containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form, SOD3 or EC-SOD, is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDa and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.

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