Catalogue number: | 10212 |
Hosts: | Rabbit |
Applications: | Immunocytochemistry, Immunohistochemistry, Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | purified recombinant human monoacylglycerol lipase |
P type: | Antibodies |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase to mobilize fatty acids from the triglyceride stores of adipocytes. MAGL has a molecular weight of ~33 kDa and exhibits a high degree of homology among human, murine, and rat at the amino acid level. The enzyme is expressed in a variety of tissues with most abundant expression in skeletal muscle and adipose tissue, suggesting a role of MAGL in monoglyceride hydrolysis in diverse tissues. Cayman |