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Monoacylglycerol Lipase Polyclonal Antibody

Cat no: 100035

Monoacylglycerol Lipase Polyclonal Antibody

Antigen: human MAGL amino acids 1-14 . Host: Rabbit . Cross Reactivity: (+) human, bovine, mouse, and rat MAGL . Application(s): IHC (formalin-fixed paraffin-embedded tissue) and WB

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SPECIFICATIONS

Catalog Number

100035

Applications

IHC, WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

human MAGL amino acids 1-14

Storage Temp

-20

Shipping Temp

-20

Additional Info

Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-Arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase (HSL) to mobilize fatty acids from the triglyceride stores of adipocytes. MAGL has a molecular weight of ~33 kDa and exhibits a high degree of homology among human, mouse, and rat at the amino acid level. The enzyme is expressed in a variety of tissues with most abundant expression in skeletal muscle and adipose tissue, suggesting a role of MAGL in monoglyceride hydrolysis in diverse tissues. Cayman Chemical's MAGL polyclonal antibody can be used for western blot and immunohistochemical (formalin-fixed paraffin-embedded tissue) analysis for MAGL on samples of human, mouse, rat, and bovine origin. Other applications for use of this antibody have not yet been tested.

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