This mouse prothrombin assay is intended for the quantitative determination of prothrombin in mouse plasma. Mouse thrombin will not be detected by the assay. The assay measures mouse prothrombin in the 1-500ng/ml range. Samples giving prothrombin levels above 500ng/ml should be diluted in blocking buffer before use. A dilution of at least 1:10,000 is recommended for measurement of prothrombin in normal mouse plasma.Prothrombin is a single-chain vitamin K dependent 579 amino acid glycoprotein zymogen. Prothrombin levels are decreased by anticoagulant therapy, vitamin K deficiency and severe liver disease. Elevated plasma prothrombin is associated with a single nucleotide change at position 20210.
Quick Search
Products 
