MPP1, ID (MPP1, DXS552E, EMP55, 55kD erythrocyte membrane protein, Membrane protein, palmitoylated 1) (FITC)

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:50-100\nFlow Cytometry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

038564-FITC

Size

200ul

Applications

ELISA, FC, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Seo, P.S., et al. Exp. Biol. Med. (Maywood) 234(3):255-262(2009)\nSeo, P.S., et al. Biochim. Biophys. Acta 1793(2):281-289(2009)\nGosens, I., et al. Hum. Mol. Genet. 16(16):1993-2003(2007)\nKusunoki, H., et al. Proteins 64(3):804-807(2006)\nFunke, L., et al. Annu. Rev. Biochem. 74, 219-245 (2005) :

Additional Info

Human

Alternative Names

MPP1, DXS552E, EMP55, 55kD erythrocyte membrane protein, Membrane protein, palmitoylated 1