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MRP4 (Multidrug Resistance-associated Protein 4, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 4, ATP Binding Cassette Sub-family C Member 4, ABCC4, bA464I2.1, Canalicular Multispecific Organic Anion Transporter ABC Superfamily, EST170205, MRP/cMOAT

Cat no: M4688-25F

MRP4 (Multidrug Resistance-associated Protein 4, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 4, ATP Binding Cassette Sub-family C Member 4, ABCC4, bA464I2.1, Canalicular Multispecific Organic Anion Transporter ABC Superfamily, EST170205, MRP/cMOAT

Applications:\nSuitable for use in Immunocytochemistry, Immunohistochemistry, Western Blot and Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nImmunocytochemistry (acetone fixed): 1:20-50 \nImmunohistochemistry (acetone fixed frozen): 1:20\nWestern Blot: 1:20-50 \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

M4688-25F

Size

1ml

Applications

FC, ICC, IHC, WB

Hosts

Rat

Reactivities

Hum, Mouse

Form

Supplied as a liquid in 0.7% BSA, 0.1% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG2a

References

1. Mrp4 confers resistance to topotecan and acts as a double agent in protecting the brain from chemotherapy Markos Leggas, Masashi Adachi, George L. Scheffer, Daxi Sun, Peter Wielinga, Guoqing Du, Kelly E. Mercer, Yanli Zhuang, John C. Panetta, Brad Johnston, Rik J. Scheper, Clinton F. Stewart, and John D. Schuetz. Mol Cell Biol, Sept. 2004, Vol. 24, No.17, p 7612-7621.

Additional Info

Recognizes human orthologue of the transporter molecule (Mrp4). Species Crossreactivity: mouse.

Alternative Names

Canalicular Multispecific Organic Anion Transporter

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