Home  >  Products  >  NACA, Recombinant, Human, aa1-215, His-tag (Nascent Polypeptide-associated Complex Subunit alpha, NAC-alpha, Alpha-NAC, Hom s 2, HSD48)

NACA, Recombinant, Human, aa1-215, His-tag (Nascent Polypeptide-associated Complex Subunit alpha, NAC-alpha, Alpha-NAC, Hom s 2, HSD48)

Cat no: 029674


Supplier: United States Biological
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NACA is member of the nascent polypeptide associated complex (NAC) alpha subunit family that participate in preventing inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Most NACA proteins localize to both nucleus as well as cytoplasm, and contain NAC-A/B (NAC-alpha/beta) and UBA (ubiquitin-associated) domains. The UBA domain is associated with proteins involved in the ubiquitin-proteasome pathway for protein degradation. Source: Recombinant corresponding to aa1-215 from human NACA, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID EEPVSKAKQS RSEKKARKAM SKLGLRQVTG VTRVTIRKSK NILFVITKPD VYKSPASDTY IVFGEAKIED LSQQAQLAAA EKFKVQGEAV SNIQENTQTP TVQEESEEEE VDETGVEVKD IELVMSQANV SRAKAVRALK NNSNDIVNAI MELTM Molecular Weight: ~25.5kD (MALDI-TOF) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 029674
Size: 100ug
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1mM DTT, 0.15M sodium chloride.
Purity: ~95% (SDS-PAGE)
References: 1. Lopez S., et al. (2005) J Cell Sci. 118(8):1595-605. 2. Stilo R., et al. (2003) 3. Biochem Biophys Res Commun. 303(4):1034-41.

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