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NAPE-PLD Polyclonal Antibody (aa 159-172)

Cat no: 10305

NAPE-PLD Polyclonal Antibody (aa 159-172)

Antigen: human NAPE-PLD amino acids 159-172 . Host: rabbit . Cross Reactivity: (+) human, mouse, and rat NAPE-PLD . Application(s): WB . NAPE-PLD catalyzes the hydrolysis of NAPE to form N-acylethanolamines (NAEs), which are involved in diverse biological processes such as inflammatory regulation, apoptosis, and tissue degeneration.

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SPECIFICATIONS

Catalog Number

10305

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

human NAPE-PLD amino acids 159-172

Storage Temp

-20

Shipping Temp

-20

Additional Info

N-acylethanolamines (NAEs) are involved in diverse biological processes such as inflammatory regulation, apoptosis, and tissue degeneration. In animals, NAEs are mainly biosynthesized via a membrane phospholipid-dependent pathway, which is the enzymatic hydrolysis of N-acyl-phosphatidylethanolamine (NAPE). The enzyme catalyzing this reaction is a phospholipase D subtype selective for NAPE named N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D (NAPE-PLD). It has been cloned from mouse, rat, and human and is 393-396 amino acids in length, with an estimated molecular weight of 46 kDa. Both NAPE-PLD mRNA and protein activity have been detected in a wide range of tissues with the highest levels in brain, kidney, and testis. In rat, NAPE-PLD activity in the brain is low in neonates and is 15-fold higher in adults, whereas the activity remains constant in the heart during development.

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