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Neuropeptide Y Y2 Receptor (NPY Y2R)

Cat no: N2176-63G

Neuropeptide Y Y2 Receptor (NPY Y2R)

Several subtypes of NPY Receptors have been described of which the cloned Y1-, Y2- and Y5-receptors, members of the superfamily of G-protein coupled receptors, appear to be the endogenous binding sites for NPY. The Y(2) receptor is the predominant Neuropeptide Y (NPY) receptor subtype in the brain. Y(2) receptor-mediated effects have been reported principally based on the observations using the C-terminal fragments of NPY. Recent studies indicate an involvement of the receptor in food intake, gastrointestinal motility, cardiovascular regulation, and neuronal excitability. \n\nApplications: \nSuitable for use in ELISA, Immunohistochemistry and Immunofluorescence. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry: 1:500-1:1000; Used on perfusion fixed tissue. Perfusion: 1) calcium-free Tyrode

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SPECIFICATIONS

Catalog Number

N2176-63G

Size

100ul

Applications

ELISA, IF, IHC

Hosts

Rabbit

Reactivities

Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. The Journal of Neuroscience 28(45): 11,583-11,592 (2008).

Additional Info

Recognizes mouse Neuropeptide Y Y2 Receptor (NPY Y2R). Species Crossreactivity: rat.

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