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Products NF-kB (p65) Monoclonal Antibody-biotin (Clone 112A1021)
| Catalogue number: | 13756 |
| Hosts: | Mouse |
| Applications: | ELISA |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | synthetic peptide corresponding to human NF-kB (p65) amino acids 526-539 |
| P type: | Antibodies|NF-.kappa.B|Intracellular Signaling |
| Isotype: | IgG1k |
| Shipping temp: | 4 |
| Storage temp: | 4 |
| Additional info: | NF-kB regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases, and inflammation. The active nuclear form of the NF-kB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65. |
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