Catalogue number: | 13757 |
Hosts: | Rabbit |
Applications: | Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | synthetic peptide corresponding to human NF-kB (p65) amino acids 2-17 |
P type: | Antibodies|NF-.kappa.B|Intracellular Signaling |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | NF-kB regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases, and inflammation. The active nuclear form of the NF-kB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65. |