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NXT1 (NTF2-like export factor 1, P15)

Cat no: N8570-04

NXT1 (NTF2-like export factor 1, P15)

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications have not been tested. \n\nRecommended Dilution: \nELISA: 1-3ug/ml \nWestern Blot: 1:500-1000\nOptimal dilutions to be determined by researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. \n\n

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SPECIFICATIONS

Catalog Number

N8570-04

Size

100ul

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2.

P Type

Mab

Purity

Purified by affinity chromatography

Isotype

IgG1

Additional Info

Recognizes human NXPT1 at ~16kD.

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