NXT2 (nuclear transport factor 2-like export factor 2) is a member of NXT family proteins that are generally involved in exporting nuclear RNA in eukaryotic cells. This protein is regulator of protein export for NES-containing proteins. Also, it associates with NXF1, NXF2, NXF3 and NXF5 and plays a role in mRNA nuclear export. NXT2 has a critical role in maintaining morphogenetic integrity of embryonic heart in vertebrate species.
Source:
Recombinant corresponding to aa1-197 from human NXT2, fused to His-tag at N-terminus, expressed in E.coli.
Molecular Weight:
~25.3kD (221aa) confirmed by MALDI-TOF
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMRKYRS HWSQGDREGY QRRSNYYEGP HTSHSSPADR TREEVVTPTL PEHTATRSQM ATSLDFKTYV DQACRAAEEF VNIYYETMDK RRRALTRLYL DKATLIWNGN AVSGLDALNN FFDTLPSSEF QVNMLDCQPV HEQATQSQTT VLVVTSGTVK FDGNKQHFFN QNFLLTAQST PNNTVWKIAS DCFRFQDWSS S
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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