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O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt

O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt

Cat no: 007688

Supplier: United States Biological
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A reactive metabolite of Lapatinib which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites. Form: Yellow Solid Melting Point: >176 degrees C (dec.) Solubility: DMSO, Methanol
Catalogue number: 007688
Size: 2.5mg
Form: Yellow Solid
Alternative names: 2-Chloro-4-[[6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinyl]amino]phenol Ditosylate;
References: He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009),

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