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Opioid Receptor, delta, Rat, aa358-372, Control Peptide

Cat no: O7030-05A

Opioid Receptor, delta, Rat, aa358-372, Control Peptide

The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.\n\nControl Peptide for Opioid Receptor, delta, O7030-05\nPeptide Sequence (linear):\nSynthetic peptide:\nTACTPSDGPGGGAAA, corresponding to amino acids 358-372 of Rat Delta Opioid Receptor.\nPurity: >99% HPLC.\n100%\nForm:\nSupplied as a lyophilized powder\nMolecular Weight:\n1233D\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Stable for 12 months at -20 degrees C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.\n\n\n

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SPECIFICATIONS

Catalog Number

O7030-05A

Size

1mg

Form

Lyophilized. Reconstitute initially in a small volume of 25% acetonitrile in water or 25% ethanol in water to make a concentrated stock solution and dilute aqueous buffer.

Purity

Purified (HPLC)

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