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OX40:Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134)

Cat no: 045123

OX40:Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134)

OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.\n\nBiological Activity:\nBlocks T cell proliferation induced by CD134L.\n\nSequence:\nHuman OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nStable for at least 6 months after receipt when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

045123

Size

50ug

Form

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.

Purity

>95% (SDS-PAGE)

Additional Info

Binds to human and mouse OX40L.

Alternative Names

TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134

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SUPPLIER INFO

Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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