p53 Cell-Based Activation/Translocation Assay Kit

The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman's p53 Cell-Based Activation/Translocation Assay provides a highly specific p53 primary monoclonal antibody together with a DyLight(TM) (product of Thermo Scientific) conjugated secondary antibody in a ready-to-use format. (-)-Nutlin-3, a potent inhibitor of Mdm2-p53 interaction, which has been shown by scientists at Cayman to cause the activation and translocation of p53 between the cytoplasm and nuclear compartments, is included as a positive control.

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SPECIFICATIONS

Catalog Number

600008

Form

96 Well

P Type

Assay Kits|Intracellular Signaling

Weight

0

Storage Temp

-20

Shipping Temp

-20

Additional Info

The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman's p53 Cell-Based Activation/Translocation Assay Kit provides a highly specific p53 primary monoclonal antibody together with a DyLightTM (product of Thermo Fisher Scientific Inc.) conjugated secondary antibody in a ready-to-use format. (-)-Nutlin-3, a potent inhibitor of Mdm2-p53 interaction, which has been shown by scientists at Cayman to cause the activation and translocation of p53 between the cytoplasm and nuclear compartments, is included as a positive control.