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p53 Total and p53 (Phospho-Ser392) Dual Staining Assay Kit

Cat no: 600060

p53 Total and p53 (Phospho-Ser392) Dual Staining Assay Kit

Cayman's p53 Total and p53 (Phospho-Ser392) Dual Staining Assay provides a pair of highly specific antibodies against total and phospho-p53 (Phospho-Ser392) together with a pair of matched DyLight(TM) (product of Thermo Scientific) conjugated secondary antibodies in a ready-to-use format. (-)-Nutlin-3, a potent inhibitor of Mdm2-p53 interaction which has been shown to cause the activation and translocation of p53 between the cytoplasm and nuclear compartments, is included as a positive control.

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SPECIFICATIONS

Catalog Number

600060

Form

96 Well

P Type

Assay Kits|Nuclear Receptors|Intracellular Signaling

Weight

0

Storage Temp

-20

Shipping Temp

-20

Additional Info

The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman's p53 Total and p53 (Phospho-Ser392) Dual Staining Assay Kit provides a pair of highly specific antibodies against total and phospho-p53 (Phospho-Ser392) together with a pair of matched DyLightTM (product of Thermo Fisher Scientific Inc.) conjugated secondary antibodies in a ready-to-use format. (-)-Nutlin-3, a potent inhibitor of Mdm2-p53 interaction which has been shown to cause the activation and translocation of p53 between the cytoplasm and nuclear compartments, is included as a positive control.

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