Catalogue number: | 600060 |
Weight: | 0 |
Form: | 96 Well |
P type: | Assay Kits|Nuclear Receptors|Intracellular Signaling |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman's p53 Total and p53 (Phospho-Ser392) Dual Staining Assay Kit provides a pair of highly specific antibodies against total and phospho-p53 (Phospho-Ser392) together with a pair of matched DyLightTM (product of Thermo Fisher Scientific Inc.) conjugated secondary antibodies in a ready-to-use format. (-)-Nutlin-3, a potent inhibitor of Mdm2-p53 interaction which has been shown to cause the activation and translocation of p53 between the cytoplasm and nuclear compartments, is included as a positive control. |