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PAF Acetylhydrolase (human) Polyclonal Antibody

Cat no: 160603

PAF Acetylhydrolase (human) Polyclonal Antibody

Antigen: human plasma PAF-AH C-terminal amino acids 420-441 . Host: rabbit . Cross Reactivity: (+) human plasma PAF-AH; (-) mouse, guinea pig, canine, and chicken PAF-AH . Application(s): WB . PAF-AH converts PAF to the biologically inactive lyso-PAF. Plasma PAF-AH is highly selective for phospholipids with very short acyl groups at the sn-2 position and is associated with lipoproteins. It has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.

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SPECIFICATIONS

Catalog Number

160603

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Enzymes|Phospholipase|Platelet-activating Factors

Weight

0

Antigen

human plasma PAF-AH C-terminal amino acids 420-441 (TNINTTNQHIMLQNSSGIEKYN){2618}

Storage Temp

-20

Shipping Temp

-20

Additional Info

AF-AH catalyzes the hydrolysis of the acetyl group at the sn-2 position of PAF to yield lyso-PAF and acetate, thereby inactivating PAF. Two main types of PAF-AH have been characterized, namely secreted (i.e., plasma) and intracellular enzymes, which are encoded on individual genes and share only 41% homology at the amino acid level. Plasma PAF-AH is a 45.4 kDa enzyme which is associated with the LDL fraction of plasma.

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