PAFAH2, ID (PAFAH2, Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2) (PE)

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

039613-PE

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Schmidt, E.B., et al. Atherosclerosis 196(1):420-424(2008)\nUmemura, K., et al. Stroke 38(3):1063-1068(2007)\nUnno, N., et al. J. Surg. Res. 134(1):36-43(2006)\nMarques, M., et al. J. Invest. Dermatol. 119(4):913-919(2002)\nMin, J.H., et al. Biochemistry 40(15):4539-4549(2001)

Additional Info

Human

Alternative Names

PAFAH2, Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2