PAK7, Active, Recombinant, Human (pak-7, pak 7, Active PAK7, PAK7, PAK, human PAK, active kinase, active kinases, recombinant PAK7, recombinant PAK, kinase activity assay, protein kinase)

The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation.\n\nSource:\nRecombinant protein corresponding to human PAK7 expressed in Sf9 insect cells.\n\nMolecular Weight: \n~130.0kD\n\nBiological Activity:\n55nmol phosphate incorporated into the Akt substrate peptide (CKRPRAASFAE) per minute per mg protein at 30 degrees C for 15 minutes using a final concentration of 50um ATP (0.83uCi/assay).\n\nStorage and Stability:\nAliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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