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PDCD1LG2, NT (PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2, Programmed cell death 1 ligand 2, Butyrophilin B7-DC, CD273) (FITC)

Cat no: 039787-FITC

PDCD1LG2, NT (PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2, Programmed cell death 1 ligand 2, Butyrophilin B7-DC, CD273) (FITC)

PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

039787-FITC

Size

200ul

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Ellis, J.S., et al. J. Immunol. 185(6):3149-3157(2010)\nPena-Cruz, V., et al. J. Invest. Dermatol. 130(9):2222-2230(2010)\nGhiotto, M., et al. Int. Immunol. 22(8):651-660(2010)\nIshizaki, Y., et al. Hum. Genet. (2010) In press :\nKassel, R., et al. Hepatology 50(5):1625-1637(2009)

Additional Info

Human

Alternative Names

PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2, Programmed cell death 1 ligand 2, Butyrophilin B7-DC, CD273

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