PDE4D (cAMP-specific 3',5'-cyclic Phosphodiesterase 4D, DPDE3, PDE43)

Cat no: P4072-03Y1

Supplier: United States Biological

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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.01-0.03ug/ml, observed in rat brain lysates on ~75kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	P4072-03Y1
Reactivities:	Human, Rat, Porcine
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Houslay, M.D., Baillie, G.S. and Maurice, D.H. cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circ Res. 2007 Apr 13;100(7):950-66.
Additional info:	Recognizes rat PDE4D. Species sequence homology: Human and porcine.

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PDE4D (cAMP-specific 3',5'-cyclic Phosphodiesterase 4D, DPDE3, PDE43)

Cat no: P4072-03Y1

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