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PEAR1 (Platelet Endothelial Aggregation Receptor 1, hPEAR1, Multiple Epidermal Growth Factor-like Domains Protein 12, Multiple EGF-like Domains Protein 12, MEGF12) (APC)

Cat no: P3129-88A

PEAR1 (Platelet Endothelial Aggregation Receptor 1, hPEAR1, Multiple Epidermal Growth Factor-like Domains Protein 12, Multiple EGF-like Domains Protein 12, MEGF12) (APC)

PEAR1, also MEGF12 is a 150kD member of the MEGF family of proteins. It is expressed principally on platelets and endothelium, and undergoes phosphorylation in response to platelet activation and adhesion. Mature human PEAR1 is a type I transmembrane protein that is 1017aa in length. It contains a 735aa extracellular region and a proline-rich 26aa cytoplasmic domain. The extracellular region shows one EMI segment aa25-103 followed by nine EGF-like repeats aa104-692. There is one potential alternate start site at Met376. Over aa21-754, human PEAR1 shares 85% and 87% aa identity with mouse and canine PEAR1.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nExcitation: 620-650nm\n\nEmission: 660-670nm\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.

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SPECIFICATIONS

Catalog Number

P3129-88A

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2B

Additional Info

Recognizes human PEAR1.

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