PerCP/Cy5.5 anti-human CD309 (VEGFR2, Flk-1)

Cat no: 338915

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

VEGF-R2, known as KDR, CD309, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.

Catalogue number:	338915
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	25 tests
Clone:	HKDR-1
Gene:	3791
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * PerCP/Cy5.5 has a maximum absorption of 482 nm and 564 nm and a maximum emission of 690 nm.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	VEGF-R2, KDR, fetal liver kinase-1 (Flk-1)